Ortho Tri-Cyclen Price Comparison

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Generic Names: Noregestimate/Ethinyl Estradiol , Generic Ortho Tri-Cyclen
Brand names: Ortho Tri-Cyclen

Ortho Tri-Cyclen Price Comparison Table

Ortho Tri-Cyclen Lo 0.18mg
ProductQtyMedical Fees
& Shipping
Price/
Qty
PriceClick to Order
Ortho Tri-Cyclen Lo 0.18mg 1 $15.00 $80.10ea $80.10
Ortho Tri-Cyclen Lo 0.18mg 1 $18.00 $87.28ea $87.28
Ortho Tri-Cyclen Lo 0.18mg 3 $15.00 $56.70ea $170.10
Ortho Tri-Cyclen Lo 0.18mg 3 $18.00 $66.65ea $199.95
Ortho Tri-Cyclen
ProductQtyMedical Fees
& Shipping
Price/
Qty
PriceClick to Order
Ortho Tri-cyclen 1 $10.95 $64.47ea $64.47
Ortho Tri-Cyclen 1 $18.00 $89.95ea $89.95
Ortho Tri-Cyclen 1 $18.00 $93.00ea $93.00
Ortho Tri-Cyclen 1 $15.00 $102.00ea $102.00
Ortho Tri-Cyclen 3 $18.00 $65.67ea $197.00
Ortho Tri-Cyclen 3 $15.00 $65.67ea $197.00
Ortho Tri-Cyclen 3 $18.00 $85.67ea $257.00
Ortho Tri-Cyclen 30 $18.00 $2.57ea $77.00
Ortho Tri-Cyclen 90 $18.00 $1.99ea $179.00
Ortho Tri-Cyclen Lo
ProductQtyMedical Fees
& Shipping
Price/
Qty
PriceClick to Order
Ortho Tri-Cyclen Lo 1 $18.00 $100.00ea $100.00
Ortho Tri-Cyclen Lo 2 $18.00 $62.50ea $125.00
Ortho Tri-Cyclen Lo 3 $18.00 $58.33ea $175.00

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Ortho Tri-Cyclen Information

Other Common Names: Cilest, Ortho-Cyclen, Evra Patch

Indication:

Ortho-Cyclen and Ortho Tri-Cyclen Tablets are indicated for the prevention of pregnancy in women who elect to use oral contraceptives as a method of contraception. Ortho Tri-Cyclen is also indicated for the treatment of moderate acne vulgaris in females, aged 15 and above, who have no known contraindications to oral contraceptive therapy, desire contraception, have achieved menarche and are unresponsive to topical anti-acne medications.

In simple terms:

Oral contraceptives, also known as "birth control pills" or "the pill," are taken to prevent pregnancy. Tri-Cyclen Tablets may also be taken to treat moderate acne in females who are able to use the pill. When taken correctly to prevent pregnancy, oral contraceptives have a failure rate of less than 1% per year when used without missing any pills. The typical failure rate of large numbers of pill users is less than 3% per year when women who miss pills are included. For most women oral contraceptives are also free of serious or unpleasant side effects. However, forgetting to take pills considerably increases the chances of pregnancy.

How Does Ortho Tri-Cyclen Work?

Oral Contraception

Combination oral contraceptives act by suppression of gonadotropins. Although the primary mechanism of this action is inhibition of ovulation, other alterations include changes in the cervical mucus(which increase the difficulty of sperm entry into the uterus) and the endometrium (which reduce the likelihood of implantation).

Receptor binding studies, as well as studies in animals and humans, have shown that norgestimate and 17-deacetyl norgestimate, the major serum metabolite, combine high progestational activity with minimal intrinsic androgenicity.Norgestimate, in combination with ethinyl estradiol, does not counteract the estrogen-induced increases in sex hormone binding globulin(SHBG), resulting in lower serumtestosterone.

Acne

Acne is a condition with a multifactorial etiology. The combination of ethinyl estradiol and norgestimate may increase sex hormone binding globulin (SHBG) and decrease free testosterone resulting in a decrease in the severity of facial acne in otherwise healthy women with this skin condition.

Ortho Tri-Cyclen Ingredients and Composition

Each of the following products is a combination oral contraceptive containing the progestational compound norgestimate and the estrogenic compound ethinyl estradiol.

Ortho Tri-Cyclen 21 Tablets and Ortho Tri-Cyclen 28 Tablets. Each white tablet contains 0.180 mg of the progestational compound, norgestimate (18,19-Dinor-17-pregn-4- en-20-yn-3-one,17-( acetyloxy)-13-ethyl-, oxime,(17a)-(+)-) and 0.035 mg of the estrogenic compound, ethinyl estradiol (19-nor-17a-pregna, 1,3,5( 10)-trien-20-yne-3,17-diol). Inactive ingredients include lactose, magnesium stearate, and pregelatinized starch.

Each light blue tablet contains 0.215 mg of the progestational compound norgestimate (18,19-Dinor-17-pregn-4- en-20-yn-3-one, 17-( acetyloxy)-13-ethyl-, oxime,( 17a)-(+)-) and 0.035 mg of the estrogenic compound, ethinyl estradiol (19-nor-17a-pregna, 1,3,5 (10)-trien-20-yne-3,17-diol). Inactive ingredients include FD&C Blue No.2 Aluminum Lake, lactose, magnesium stearate, and pregelatinized starch.

Each blue tablet contains 0.250 mg of the progestational compound norgestimate (18,19-Dinor-17-pregn-4- en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, oxime,( 17a)-(+)-) and 0.035 mg of the estrogenic compound, ethinyl estradiol (19-nor-17a-pregna, 1,3,5 (10)-trien-20-yne-3,17-diol). Inactive ingredients include FD&C Blue No.2 Aluminum Lake, lactose, magnesium stearate, and pregelatinized starch.

Each green tablet in the Ortho Tri-Cyclen 28 package contains only inert ingredients, as follows: D&C Yellow No.10 Aluminum Lake, FD&C Blue No.2 Aluminum Lake, lactose, magnesium stearate, microcrystalline cellulose and pregelatinized starch.

Ortho-Cyclen 21 Tablets and Ortho-Cyclen 28 Tablets. Each blue tablet contains 0.250 mg of the progestational compound, norgestimate (18,19-Dinor-17-pregn-4- en-20-yn-3-one,17-(acetyloxy)-13-ethyl-,oxime,(17a)-(+)-) and 0.035 mg of the estrogenic compound, ethinyl estradiol (19-nor-17a-pregna,1,3,5(10)-trien-20-yne-3,17-diol). Inactive ingredients include FD&C Blue No.2 Aluminum Lake, lactose, magnesium stearate, and pregelatinized starch.

Each green tablet in the Ortho-Cyclen 28 package contains only inert ingredients, as follows: D&C Yellow No.10 Aluminum Lake, FD&C Blue No.2 Aluminum Lake, lactose, magnesium stearate, microcrystalline cellulose and pregelatinized starch.

How To Take Ortho Tri-Cyclen and Ortho Tri-Cyclen Dosage and Administration

To achieve maximum contraceptive effectiveness, Ortho Tri-Cyclen Tablets and Ortho-Cyclen Tablets must be taken exactly as directed and at intervals not exceeding 24 hours. Ortho Tri-Cyclen and Ortho-Cyclen are available in the DIALPAK Tablet Dispenser which is preset for a Sunday Start. Day 1 Start is also provided.

21-Day Regimen (Sunday Start)

When taking Ortho Tri-Cyclen 21 and Ortho-Cyclen 21, the first tablet should be taken on the first Sunday after menstruation begins. If period begins on Sunday, the first tablet is taken on that day. One tablet is taken daily for 21 days. For subsequent cycles, no tablets are taken for 7 days, then a tablet is taken the next day (Sunday). For the first cycle of a Sunday Start regimen, another method of contraception should be used until after the first 7 consecutive days of administration. If the patient misses one (1) active tablet in Weeks 1, 2, or 3, the tablet should be taken as soon as she remembers. If the patient misses two (2) active tablets in Week 1 or Week 2, the patient should take two (2) tablets the day she remembers and two (2) tablets the next day; and then continue taking one (1) tablet a day until she finishes the pack. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing pills. If the patient misses two (2) active tablets in the third week or misses three (3) or more active tablets in a row, the patient should continue taking one tablet every day until Sunday. On Sunday the patient should throw out the rest of the pack and start a new pack that same day. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing pills.

Complete instructions to facilitate patient counseling on proper pill usage may be found in the Detailed Patient Labeling (" How to Take the Pill" section).

21-Day Regimen (Day 1 Start)

The dosage of Ortho Tri-Cyclen 21 and Ortho-Cyclen 21, for the initial cycle of therapy is one tablet administered daily from the 1st day through the 21st day of the menstrual cycle, counting the first day of menstrual flow as "Day 1." For subsequent cycles, no tablets are taken for 7 days, then a new course is started of one tablet a day for 21 days. The dosage regimen then continues with 7 days of no medication, followed by 21 days of medication, instituting a three-weeks-on, one-week-off dosage regimen.

If the patient misses one (1) active tablet in Weeks 1, 2, or 3, the tablet should be taken as soon as she remembers. If the patient misses two (2) active tablets in Week 1 or Week 2, the patient should take two (2) tablets the day she remembers and two (2) tablets the next day; and then continue taking one (1) tablet a day until she finishes the pack. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing pills. If the patient misses two (2) active tablets in the third week or misses three (3) or more active tablets in a row, the patient should throw out the rest of the pack and start a new pack that same day. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing Ortho Tri-Cyclen pills.

Complete instructions to facilitate patient counseling on proper pill usage may be found in the Detailed Patient Labeling (" How to Take the Pill" section).

28-Day Regimen (Sunday Start)

When taking Ortho Tri-Cyclen 28 and Ortho-Cyclen 28 the first tablet should be taken on the first Sunday after menstruation begins. If period begins on Sunday, the first tablet should be taken that day. Take one active tablet daily for 21 days followed by one green tablet daily for 7 days. After 28 tablets have been taken, a new course is started the next day (Sunday). For the first cycle of a Sunday Start regimen, another method of contraception should be used until after the first 7 consecutive days of Ortho Tri-Cyclen administration.

If the patient misses one (1) active tablet in Weeks 1, 2, or 3, the tablet should be taken as soon as she remembers. If the patient misses two (2) active tablets in Week 1 or Week 2, the patient should take two (2) tablets the day she remembers and two (2) tablets the next day; and then continue taking one (1) tablet a day until she finishes the pack. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing pills. If the patient misses two (2) active tablets in the third week or misses three (3) or more active tablets in a row, the patient should continue taking one tablet every day until Sunday. On Sunday the patient should throw out the rest of the pack and start a new pack that same day. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing Ortho Tri-Cyclen pills.

28-Day Regimen (Day 1 Start)

The dosage of Ortho Tri-Cyclen 28 and Ortho-Cyclen 28, for the initial cycle of therapy is one active tablet administered daily from the 1st day through the 21st day of the menstrual cycle, counting the first day of menstrual flow as "Day 1" followed by one green tablet daily for 7 days. Tablets are taken without interruption for 28 days. After 28 tablets have been taken, a new course is started the next day.

If the patient misses one (1) active tablet in Weeks 1, 2, or 3, the tablet should be taken as soon as she remembers. If the patient misses two (2) active tablets in Week 1 or Week 2, the patient should take two (2) tablets the day she remembers and two (2) tablets the next day; and then continue taking one (1) tablet a day until she finishes the pack. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing pills. If the patient misses two (2) active tablets in the third week or misses three (3) or more active tablets in a row, the patient should throw out the rest of the pack and start a new pack that same day. The patient should be instructed to use a back-up method of birth control if she has sex in the seven (7) days after missing Ortho Tri-Cyclen pills.

The use of Ortho Tri-Cyclen and Ortho-Cyclen for contraception may be initiated 4 weeks postpartum in women who elect not to breast feed. When the tablets are administered during the postpartum period, the increased risk of thromboembolic disease associated with the postpartum period must be considered.

Dosage of Ortho Tri-Ciclen for Acne Treatment

The timing of initiation of dosing with OOrtho Tri-Cyclen for acne should follow the guidelines for use of OOrtho Tri-Cyclen as an oral contraceptive. The dosage regimen for Ortho Tri-Cyclen for treatment of facial acne, as available in a DIALPAK Tablet Dispenser, utilizes a 21-day active and a 7-day placebo schedule. Take one active tablet daily for 21 days followed by one green tablet for 7 days. After 28 tablets have been taken, a new course is started the next day.

If you suspect a Ortho Tri-Cyclen Overdose

Serious ill effects have not been reported following ingestion of large doses of oral contraceptives by young children. Overdosage may cause nausea and withdrawal bleeding in females. In case of overdosage, contact your health care provider or pharmacist.

If You Miss a Dose of Ortho Tri-Cyclen

Ortho Tri-Cyclen:

If you miss 1 white, light blue, or blue "active" pill:

  1. Take it as soon as you remember. Take the next pill at your regular time. This means you may take 2 pills in 1 day.
  2. You do not need to use a back-up birth control method if you have sex.

If you miss 2 white or light blue "active" pills in a row in week 1 or week 2 of your pack:

  1. Take 2 pills on the day you remember and 2 pills the next day.
  2. Then take 1 pill a day until you finish the pack.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

If you miss 2 blue "active" pills in a row in the 3rd week:

  1. If you are a Sunday Starter: Keep taking 1 pill every day until Sunday. On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day. If you are a Day 1 Starter: THROW OUT the rest of the pill pack and start a new pack that same day.
  2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a row, call your doctor or clinic because you might be pregnant.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

If you miss 3 OR MORE white, light blue, or blue "active" pills in a row (during the first 3 weeks):

  1. If you are a Sunday Starter: Keep taking 1 pill every day until Sunday. On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day. If you are a Day 1 Starter: THROW OUT the rest of the pill pack and start a new pack that same day.
  2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a row, call your doctor or clinic because you might be pregnant.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

Ortho Tri-Cyclen:

If you miss 1 blue "active" pill:

  1. Take it as soon as you remember. Take the next pill at your regular time. This means you may take 2 pills in 1 day.
  2. You do not need to use a back-up birth control method if you have sex.

If you miss 2 blue "active" pills in a row in week 1 OR week 2 of your pack:

  1. Take 2 pills on the day you remember and 2 pills the next day.
  2. Then take 1 pill a day until you finish the pack.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

If you miss 2 blue "active" pills in a row in THE 3RD week:

  1. If you are a Sunday Starter: Keep taking 1 pill every day until Sunday. On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day. If you are a Day 1 Starter: THROW OUT the rest of the pill pack and start a new pack that same day.
  2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a row, call your doctor or clinic because you might be pregnant.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

If you miss 3 OR MORE blue "active" pills in a row (during the first 3 weeks):

  1. If you are a Sunday Starter: Keep taking 1 pill every day until Sunday. On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day. If you are a Day 1 Starter: THROW OUT the rest of the pill pack and start a new pack that same day.
  2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a row, call your doctor or clinic because you might be pregnant.
  3. You MAY BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use another birth control method (such as condoms, foam, or sponge) as a back-up method for those 7 days.

Contraindications to Ortho Tri-Cyclen

Oral contraceptives should not be used in women who currently have the following conditions:

Ortho Tri-Cyclen Side Effects

An increased risk of the following serious adverse reactions has been associated with the use of oral contraceptives:

The following adverse reactions have been reported in patients receiving oral contraceptives and are believed to be drug-related:

The following adverse reactions have been reported in users of oral contraceptives and the association has been neither confirmed nor refuted:

Ortho Tri-Cyclen Precautions and Contraindications

Be sure to discuss any medical condition you may have with your health care provider. Your health care provider will take a medical and family history before prescribing oral contraceptives and will examine you. The physi-cal examination may be delayed to another time if you request it and the health care provider believes that it is a good medical practice to postpone it. You should be reexamined at least once a year while taking oral contraceptives. Your pharmacist should have given you the detailed patient information labeling which gives you further information which you should read and discuss with your health care provider.

If any of these adverse effects occur while you are taking oral contraceptives, call your doctor immediately:

Ortho Tri-Cyclen Drug Interactions

Reduced efficacy and increased incidence of breakthrough bleeding and menstrual irregularities have been associated with concomitant use of rifampin. A similar association, though less marked, has been suggested with barbiturates, phenylbutazone, phenytoin sodium, carbamazepine, and possibly with griseofulvin, ampicillin and tetracyclines.

Certain drugs may interact with birth control pills to make them less effective in preventing pregnancy or cause an increase in breakthrough bleeding. Such drugs include rifampin, drugs used for epilepsy such as barbiturates (for example, phenobarbital), anticonvulsants such as carbamazepine (Tegretol is one brand of this drug), phenytoin (Dilantin is one brand of this drug), phenylbutazone (Butazolidin is one brand) and possibly certain antibiotics. You may need to use additional contraception when you take drugs which can make oral contraceptives less effective.

Ortho Tri-Cyclen Experiences and Results

Oral contraceptives are highly effective. The table below lists the typical accidental pregnancy rates for users of combination oral contraceptives and other methods of contraception. The efficacy of these contraceptive methods, except sterilization, depends upon the reliability with which they are used. Correct and consistent use of methods can result in lower failure rates.

% of Women Experiencing an Accidental Pregnancy in the First Year of Continuous Use

MethodLowest ExpectedTypical
No Contraceptive8585
Oral contraceptives3
combined0.1N/ A
progestin only0.5N/ A
Diaphragm with spermicidal cream or jelly618
Spermicides alone (foams, creams, gels, jellies, vaginal suppositories, and vaginal film)621
Vaginal sponge nulliparous918
parous2036
Implant0.090.09
Injection: depot medroxyprogesterone acetate0.30.3
IUD progesterone1.52.0
copper T 380A0.60.8
Condom without spermicides female521
male312
Cervical Cap with spermicidal cream or jelly nulliparous918
parous2636
Periodic abstinence (all methods)1- 920
Female sterilization0.40.4
Male sterilization0.100.15

Ortho Tri-Cyclen Clinical Trials and Studies

In clinical trials with Ortho-Cyclen, 1,651 subjects completed 24,272 cycles and a total of 18 pregnancies were reported. This represents an overall use-efficacy (typical user efficacy) pregnancy rate of 0.96 per 100 women-years. This rate includes patients who did not take the drug correctly.

In four clinical trials with Ortho Tri-Cyclen, the use-efficacy pregnancy rate ranged from 0.68 to 1.47 per 100 women-years. In total, 4,756 subjects completed 45,244 cycles and a total of 42 pregnancies were reported. This represents an overall use-efficacy rate of 1.21 per 100 women-years. One of these 4 studies was a randomized comparative clinical trial in which 4,633 subjects completed 22,312 cycles. Of the 2,312 patients on Ortho Tri-Cyclen, 8 pregnancies were reported. This represents an overall use-efficacy pregnancy rate of 0.94 per 100 women-years.

Oral Contraceptives and Smoking

Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use oral contraceptives are strongly advised not to smoke.

Taking Ortho Tri-Cyclen during Pregnancy or Breast-feeding

If you are breast feeding, consult your doctor before starting oral contraceptives. Some of the drug will be passed on to the child in the milk. A few adverse effects on the child have been reported, including yellowing of the skin (jaundice) and breast enlargement. In addition, oral contraceptives may decrease the amount and quality of your milk. If possible, do not use oral contraceptives while breast feeding. You should use another method of contraception since breast feeding provides only partial protection from becoming pregnant and this partial protection decreases significantly as you breast feed for longer periods of time. You should consider starting oral contraceptives only after you have weaned your child completely.

Additional Notes

Ortho Tri-Cyclen Tablets Ortho-Cyclen Tablets (norgestimate/ethinyl estradiol) Prescribing Information Patients should be counseled that this product does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

Ortho Tri-Cyclen FAQ

FAQ. Does Zantrex-3 interact with or make my birth control pills (Ortho-Tri-Cyclen Lo) less effective in any way?

This question was sent in by a visitor:

Hello, will Zantrex-3 interact with or make my birth control pills (Ortho-Tri-Cyclen Lo) less effective in any way? - Justina, NC

A. Justina, as far as is known, Zantrex-3 should not interact with Orth Tri-Cyclen in any way, since they work in different ways and do not interact with each other. Orhto-Tri Cyclen works by utilising hormonal systems, while Zantrex-3 fuels various metabolic processes, attempting to speed them up and induce thermogenesis.

However, if you remain unsure - consult your doctor.

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Credits for Ortho Tri-Cyclen Information

Ortho Tri-Cyclen information on this page is copyright by Drug Information at Pharma-Help.com, reprinted with Permission. All Rights Reserved. Other pages with reprint permission include Ortho Tri-Cyclen.

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