Table Of Contents
- Nordette Price Comparison Table
- Nordette Information
- Nordette Ingredients and Composition
- How Does Nordette Work?
- How To Take Nordette and Nordette Dosage and Administration
- Nordette Pill Identification / ID and Appearance
- If you suspect a Nordette Overdose
- Nordette Side Effects
- Nordette Warnings
- Nordette Precautions and Contraindications
- Contraindications to Nordette
- Taking Nordette during Pregnancy or Breast-feeding
- Storing Nordette
- Credits for Nordette Information
Nordette Price Comparison Table
| Product | Qty | Price | Medical Fees & Shipping | Price/ Qty | Click to Order |
|---|---|---|---|---|---|
| Nordette | 28 | $98.00 | $18.00 | $3.50 | Buy from Billing-md |
| Nordette | 84 | $160.00 | $18.00 | $1.90 | Buy from Billing-md |
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Nordette Information
Brand Name: Nordette
Other Common Names: Nordette 28
Nordette is intended to prevent pregnancy when you have experienced known or suspected contraceptive failure (e.g., broken condom) or have not used contraception. The first dose of Nordette should be taken as soon as possible but within 72 hours of unprotected sex. Nordette is meant for emergency use only and not as a regular method of birth control. Like all oral contraceptives, Nordette does not protect against infection with HIV (the virus which causes AIDS) and other sexually transmitted diseases.
Nordette Indications
Nordette (ethinyl estradiol, levonorgestrel) is indicated for the prevention of pregnancy in women after known or suspected contraceptive failure or unprotected intercourse. To obtain optimal efficacy, use of these pills should begin as soon as possible but within 72 hours of intercourse.
Nordette Efficacy
If one hundred women used Nordette correctly in one month, about two women would become pregnant after a single act of intercourse. If no contraception is used about eight women would become pregnant after a single act of intercourse. Therefore, the use of Nordette results in a 75% reduction in the number of pregnancies to be expected if no ECPs were used after unprotected intercourse. Notably, some Nordette clinical trials have shown that efficacy was greatest when ECPs were taken within 24 hours of unprotected intercourse, decreasing somewhat during each subsequent 24-hour period.
Nordette Ingredients and Composition
Each Nordette tablet contains 0.15 mg of levongestrel, a totally synthetic progestogen, and 0.03 mg of ethinyl estradiol.
The inactive Nordette ingredients are:
- cellulose
- FD&C yellow 6
- lactose
- magnesium stearate
- polacrillin potassium.
Nordette tablets are round, light orange and marked with "WYETH" and "75".
How Does Nordette Work?
Nordette acts primarily by inhibiting ovulation. Nordette may also act by altering tubal transport of sperm and/or ova (thereby inhibiting fertilization), and/or possibly altering the endometrium (thereby inhibiting implantation).
This is why Nordette will not work if you are already pregnant.
How To Take Nordette and Nordette Dosage and Administration
The Preven Emergency Contraceptive Kit contains a pregnancy test. This test can be used to verify an existing pregnancy resulting from intercourse that occurred earlier in the current menstrual cycle or the previous cycle. If a positive pregnancy result is obtained, the patient should not take the pills in the Preven Kit.
The initial two Nordette pills must be taken as soon as possible but within 72 hours of unprotected intercourse. This is followed by the second dose of two pills 12 hours later. The patient should be instructed that if she vomits within one hour of taking either dose of the medication, she should contact her healthcare professional to discuss whether to repeat that Nordette dose or to take an antinausea medication. ECPs are not indicated for ongoing pregnancy protection and should not be used as a woman's routine form of contraception.
Nordette Pill Identification / ID and Appearance
Each Nordette pill contains 0.25 mg levonorgestrel and 0.05 mg ethinyl estradiol. The pills are marked with a G on one side and the numerals 891 on the other.
Nordette tablets are round, light orange and marked with "WYETH" and "75".
If you suspect a Nordette Overdose
There have been no reports of serious ill effects from Nordette overdosage, including ingestion by children.
Nordette Side Effects
You may experience the following Nordette side effects:
- Nausea and Vomiting
- About half of the women who take ECPs such as Nordette experience temporary nausea. It is usually mild and stops within a few hours, but may continue for up to 1 or 2 days. About 20% of women who take ECPs such as Nordette may vomit. If you vomit within one hour after taking either dose of ECPs, call your healthcare professional to discuss whether to repeat the dose or to take antinausea medicine.
- Menstrual Cycle Disturbances
- It has been reported that following ECP use, about 75% of women experience a normal period on time. However, irregular vaginal bleeding or spotting may occur after taking Nordette. Such patterns of bleeding may be temporary and usually do not indicate any serious problems. Menstrual bleeding may begin a few days earlier or later than would have been expected. Your menstrual wflow may be heavier or lighter than usual. If the bleeding lasts longer than your normal period or if bleeding does not start within 21 days after treatment, talk to your healthcare professional.
- Breast Tenderness
- Breast tenderness occurs in approximately 10% to 20% of women studied while taking Nordette regimen.
- Headaches
- Headaches occur in up to 10% of women studied while taking the Nordette regimen.
- Abdominal Pain
- Abdominal/pelvic pain occurs in approximately 1% of women taking the ECP regimen.
- Dizziness
- Dizziness is occasionally reported.
Nordette side effects usually subside within a day or two after treatment is completed.
You may experience additional Nordette side effects.
Nordette Warnings
Ethinyl estradiol; levonorgestrel, used in Nordette, are combination oral contraceptive (COC) pills. The following are the warnings given for daily cyclical combination oral contraceptive pill use (1 pill each day for 21 days of a 28-day cycle). It is not known whether these warnings also apply to the ECP regimen of four oral contraceptive pills taken within a 12-hour period.
Important
Cigarette smoking increases the risk of serious cardiovascular side effects from COC use. This risk increases with age and heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use Nordette should be strongly advised not to smoke.
Cardiovascular Disease (CVD)
Nordette use is associated with a small increase in the incidence of cardiovascular disease (CVD), primarily because of an increased risk of thrombosis rather than through an atherogenic mechanism. The degree of risk appears to be related primarily to the estrogen dosage. This increased risk is limited to the period during COC use and disappears upon cessation of use. Because the incidence of CVD is low during the reproductive years, the absolute risk attributable to COC use is quite small.
Deep Vein Thrombosis, Pulmonary Embolism
Use of COCs is associated with a low absolute risk of venous thromembolism which is nonetheless 3- to 6-fold higher than that among non-users. Smoking does not appear to be a risk factor.
The presence of factor V Leiden mutation and other hereditary coagulation disorders increases the risk of thromboembolic disease.
Nordette use is contraindicated for women who have deep vein thrombosis or pulmonary embolism and for those who have a history of these conditions.
Women who are immobilized for prolonged periods because of major surgery (or illness or injury) should not use COCs. For women undergoing major surgery without prolonged immobilization, the advantages of COC use generally outweigh the risk.
Nordette use should preferably not begin until two to three weeks postpartum, because of the risk of thrombosis.
Cerebrovascular Disease
In women who do not smoke and do not have hypertension, the risk of ischemic stroke in users of COCs is increased about 1.5 fold compared with non-users. The likelihood of hemorrhagic stroke is not increased among users of low-dose combined COCs who are under 35 years old and do not smoke or have hypertension. Women who have a history of stroke should not use COCs.
Ischemic Heart Disease
The likelihood of myocardial infarction is not increased among young women who use COCs and do not smoke or have hypertension or diabetes. Smokers older than 35 should not take COCs. Women who currently have ischemic heart disease, or who have a history of this disease, should not use Nordette.
Valvular Heart Disease
Nordette use is contraindicated for women whose valvular heart disease is complicated by such factors as pulmonary hypertension, atrial fibrillation, or history of sub-acute bacterial encarditis. COC use may be acceptable for women with uncomplicated valvular heart disease.
Elevated Blood Pressure
For women with an elevation in blood pressure (160+/100+mmHg), COC use would present an unacceptable health risk, and COCs should not be used. Similarly, hypertensive women with vascular disease should not use COCs.
Ocular Lesions
There have been clinical case reports of retinal thrombosis associated with the use of oral contraceptives. Oral contraceptives should be discontinued if there is unexplained partial or complete loss of vision; onset of proptosis or diplopia; papilledema; or retinal vascular lesions.
Carbohydrate Metabolism
For women with diabetes (both insulin-dependent and non-insulin dependent), who do not have vascular involvement, the advantages of COC use generally outweigh the risks, particularly the risks associated with pregnancy. The major concerns are vascular disease and added risk of thrombosis, although COC use by diabetic women appears to have only minimal effects on lipid metabolism and hemostasis. For diabetic women with nephropathy, retinopathy, neuropathy, or other vascular involvement, the risk-benefit ratio depends on the severity of the condition.
Headaches
For women with severe, recurrent headaches, including migraine headaches, the appropriateness of using COCs depends on the presence or absence of focal neurologic symptoms. These symptoms may reflect an increased risk of stroke and COC use is contraindicated in patients in whom they are present. The onset or exacerbation of migraines or the development of severe headache with focal neurological symptoms, which are recurrent or persistent, requires discontinuation of COC use and evaluation of the cause.
U nexplained Vaginal Bleeding
Women who have unexplained vaginal bleeding, suggestive of an underlying pathological condition or pregnancy, should be evaluated prior to initiation of COC use in order to avoid confusion of the pathological bleeding with COC side effects.
Liver Disease
Because steroid hormones are metabolized by the liver, women taking COCs may experience adverse hepatobiliary effects. Although case-control studies have indicated that the risk of both benign and malignant liver tumors may be slightly increased by COC use, the incidence potentially attributable to COCs in the United States is minimal because the dooisease is very rare.
Women who currently have active liver disease should not use Nordette.
Ectopic Pregnancy
Ectopic as well as intrauterine pregnancy may occur in contraceptive failures.
Nordette Precautions and Contraindications
Nordette is not effective if the woman is pregnant; it acts primarily by inhibiting ovulation. It may also act by altering tubal transport of sperm and/or ova (thereby inhibiting fertilization), and/or possibly altering the endometrium (thereby inhibiting implantation).
Contraindications to Nordette
Ethinyl estradiol; levonorgestrel are combination oral contraceptive (COC) pills - Nordette. The following are the known contraindications of daily cyclical combination oral contraceptive pill use (1 pill each day for 21 days of a 28-day cycle). It is not known whether these contraindications also apply to the ECP regimen of four oral contraceptive pills taken within a 12-hour period.
- Known or suspected pregnancy.
- Pulmonary embolism (current or history).
- Ischemic heart disease (current or history).
- History of cerebrovascular accidents.
- Valvular heart disease with complications.
- Severe hypertension.
- Diabetes with vascular involvement.
- Headaches with focal neurological symptoms.
- Major surgery with prolonged immobilization.
- Known or suspected carcinoma of the breast or personal history of breast cancer.
- Liver tumors (benign and malignant) active liver disease.
- Heavy smoking (>15 cigarettes per day) and over the age of 35.
In addition, use is contraindicated in women who are known to be hypersensitive to any component of this product.
Taking Nordette during Pregnancy or Breast-feeding
If you are breast-feeding, you should not take Nordette. COCs have been reported in the milk of breast feeding mothers with no apparent clinical significance; long-term follow-up of children whose mothers used COCs while breast-feeding has shown no deleterious effects.
Storing Nordette
Store Nordette at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).
Credits for Nordette Information
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